T3SS-IN-1

T3SS-IN-1 (compound B9) is a potent inhibitor of type III secretion system (T3SS) inhibitor. T3SS-IN-1 can also inhibits hpa1 promoter activity and harpin protein expression without affecting bacterial growth[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/t3ss-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC)/C([N+]([O-])=O)=C/C1=CC=C(C2=CC=CC(OC)=C2)O1

Molecular Formula

C16H15NO6

Molecular Weight

317.29

References & Citations

[1]Gao D, et, al. Novel Ethyl-3-Aryl-2-Nitroacrylate Derivatives as Potential T3SS Inhibitors against Xanthomonas oryzae pv. oryzae on Rice. J Agric Food Chem. 2023 Jun 21;71 (24) :9291-9301.