DDO-8926
DDO-8926 is a potent and selective BET inhibitor that can significantly reduce mechanical hypersensitivity by inhibiting the expression of pro-inflammatory cytokines and reducing excitability for neuropathic pain research[1].
Product Specifications
CAS Number
3017181-08-4
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ddo-8926.html
Solubility
10 mM in DMSO
Smiles
CC1=NN(C(C)=C1C2=C(C(C3=C4NC=NC4=NC=C3)=CC(NS(CC)(=O)=O)=C2)F)C
Molecular Formula
C20H21FN6O2S
Molecular Weight
428.48
References & Citations
[1]Xuetao Chen, et al. Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. J Med Chem. 2023 Jul 13;66 (13) :8725-8744.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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