FAP-IN-1
FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor with an IC50 value of 3.3 nM. FAP-IN-1 can be used for the research of cancer[1].
Product Specifications
CAS Number
2956858-96-9
UNSPSC
12352005
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fap-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=NC2=C1C=CC=C2NC([C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCNC(CN3CCN(CCN(CCN(CC3)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)NC(C4=C5C=CC=CC5=CC=C4)=O)=O)NCC(N6[C@](C#N)(CC(F)(C6)F)[H])=O
Molecular Formula
C65H88F2N12O18
Molecular Weight
1363.46
References & Citations
[1]Wang Y, et al. High Affinity and FAP-Targeted Radiotracers: A Potential Design Strategy to Improve the Pharmacokinetics and Tumor Uptake for FAP Inhibitors. J Med Chem. 2023 Jul 13;66 (13) :8614-8627.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog