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FAP-IN-1

FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor with an IC50 value of 3.3 nM. FAP-IN-1 can be used for the research of cancer[1].

Product Specifications

CAS Number

2956858-96-9

UNSPSC

12352005

Target

FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fap-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=NC2=C1C=CC=C2NC([C@@H](CCCCNC(CCOCCOCCOCCOCCOCCOCCNC(CN3CCN(CCN(CCN(CC3)CC(O)=O)CC(O)=O)CC(O)=O)=O)=O)NC(C4=C5C=CC=CC5=CC=C4)=O)=O)NCC(N6[C@](C#N)(CC(F)(C6)F)[H])=O

Molecular Formula

C65H88F2N12O18

Molecular Weight

1363.46

References & Citations

[1]Wang Y, et al. High Affinity and FAP-Targeted Radiotracers: A Potential Design Strategy to Improve the Pharmacokinetics and Tumor Uptake for FAP Inhibitors. J Med Chem. 2023 Jul 13;66 (13) :8614-8627.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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