HDAC-IN-58
Product Specifications
UNSPSC Description
HDAC-IN-58 is a HDAC inhibitor. HDAC-IN-58 has HDAC6-specific inhibition activity with an IC50 value of 2.06 nM. HDAC-IN-58 can be used for the research of chronic diseases, including neurodegenerative and psychiatric conditions[1].
Target Antigen
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hdac-in-58.html
Solubility
10 mM in DMSO
Smiles
CS(=O)(N(C1=CC=CC(Cl)=C1)CC2=NC=C(C3=NN=C(C(F)F)O3)C=C2)=O
Molecular Weight
414.81
References & Citations
[1]Motlová L, et al. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6). ACS Chem Biol. 2023 Jul 21;18(7):1594-1610.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149859/HDAC-IN-58-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149859/
Clinical Information
No Development Reported
CAS Number
2071224-39-8
Curated Selection
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