β-catenin-IN-7

β-catenin-IN-7 (Compound 9) is a β-catenin inhibitor. β-catenin-IN-7 inhibits the interaction between β-catenin and Tcf-4, and inhibits Wnt-dependent target gene expression. β-catenin-IN-7 has anti-cancer activity[1].

Product Specifications

CAS Number

[2952779-17-6]

UNSPSC

12352005

Target

Wnt

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/β-catenin-in-7.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(Br)C=C1)(NC2=CC=C(C3=NC=CC=C3)C=C2)=O

Molecular Formula

C17H13BrN2O2S

Molecular Weight

389.27

References & Citations

[1]Nalli M, et al. Novel N- (Heterocyclylphenyl) benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent. ACS Pharmacol Transl Sci. 2023 Jul 3;6 (7) :1087-1103.