β-catenin-IN-7
Product Specifications
UNSPSC Description
β-catenin-IN-7 (Compound 9) is a β-catenin inhibitor. β-catenin-IN-7 inhibits the interaction between β-catenin and Tcf-4, and inhibits Wnt-dependent target gene expression. β-catenin-IN-7 has anti-cancer activity[1].
Target Antigen
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/β-catenin-in-7.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(Br)C=C1)(NC2=CC=C(C3=NC=CC=C3)C=C2)=O
Molecular Weight
389.27
References & Citations
[1]Nalli M, et al. Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent. ACS Pharmacol Transl Sci. 2023 Jul 3;6(7):1087-1103.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149858/β-catenin-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149858/
Clinical Information
No Development Reported
CAS Number
2952779-17-6
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