Anti-osteoporosis agent-3
Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption[1].
Product Specifications
CAS Number
[2944463-16-3]
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-osteoporosis-agent-3.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)C1=CC(NCC(NC2=C(C=CC=C2)SC3=CC=CC=C3)=O)=CC=C1
Molecular Formula
C22H20N2O3S
Molecular Weight
392.47
References & Citations
[1]Chen Z, et al. Discovery of PMSA Derivative 11 as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis In Vitro and In Vivo. J Med Chem. 2023 May 25;66 (10) :6766-6781.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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