P38 Kinase inhibitor 5
P38 Kinase inhibitor 5 (AA6) is a potent p38 kinase inhibitor with an IC50 of 403.57 nM. p38 Kinase inhibitor 5 has anti-inflammatory activity[1].
Product Specifications
CAS Number
2929285-29-8
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/p38-kinase-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C)C=C1C)C(NC(CN2C=C(C(F)(F)F)N=C2)=O)CC3=CC=CC=C3
Molecular Formula
C23H23F3N4O2
Molecular Weight
444.45
References & Citations
[1]Archana Awasthi, et al. Synthesis, In Silico Studies, and In Vitro Anti-Inflammatory Activity of Novel Imidazole Derivatives Targeting p38 MAP Kinase. ACS Omega. 2023 May 12;8 (20) :17788-17799.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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