S-F24

S-F24 is an antifungal agent with excellent broad-spectrum. S-F24 inhibits CYP3A4 with an IC50 value of 0.4 μM. S-F24 displays a good safety profile with high selectivity, low hemolytic effects, and low tendency to induce resistance. S-F24 can be used for research on fungal infections[1].

Product Specifications

CAS Number

[2946669-78-7]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/s-f24.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(C(F)=C1)[C@](CN2C=NC=N2)(O)CN3CCN(CC3)CCN4C5=C(C=C4)C=C(Br)C=C5

Molecular Formula

C25H27BrF2N6O

Molecular Weight

545.42

References & Citations

[1] Zhu P, et al. Novel Triazoles with Potent and Broad-Spectrum Antifungal Activity In Vitro and In Vivo. J Med Chem. 2023 Jun 8;66 (11) :7497-7515.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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