AKT-IN-17

AKT-IN-17 is a AKt inhibitor. AKT-IN-17 inhibits AKt in A549 cells, leading to Apoptosis. AKT-IN-17 is a potential anti-NSCLC agents, can be used in non-small cell lung cancer study[1].

Product Specifications

UNSPSC

12352005

Target

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/akt-in-17.html

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=CC=C(N2CCCCC2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3

Molecular Formula

C21H21ClN4O2S

Molecular Weight

428.94

References & Citations

[1]Erdönmez B, et al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8 (22) :20056-20065.