Antitumor agent-113

Antitumor agent-113 shows cytotoxic effects on A549 cells with IC50 value of 46.60 μM and induces apoptosis. Antitumor agent-113 can be used in non-small cell lung cancer study[1].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-113.html

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=CC=C(N2CCN(C)CC2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3

Molecular Formula

C21H22ClN5O2S

Molecular Weight

443.95

References & Citations

[1]Erdönmez B, et.al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8 (22) :20056-20065.