Antitumor agent-113
Antitumor agent-113 shows cytotoxic effects on A549 cells with IC50 value of 46.60 μM and induces apoptosis. Antitumor agent-113 can be used in non-small cell lung cancer study[1].
Product Specifications
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-113.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=C(N2CCN(C)CC2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3
Molecular Formula
C21H22ClN5O2S
Molecular Weight
443.95
References & Citations
[1]Erdönmez B, et.al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8 (22) :20056-20065.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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