Antitumor agent-112
Antitumor agent-112 (compound 3a) is a potent antitumor agent. Antitumor agent-112 induces apoptosis. Antitumor agent-112 has cytotoxic activity on A549 cells with an IC50 value of 91.35 μM[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-112.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=C(N(C)C)C=C1)CSC2=NC3=CC(Cl)=CC=C3O2
Molecular Formula
C18H17ClN4O2S
Molecular Weight
388.87
References & Citations
[1]Erdönmez B, et, al. Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy. ACS Omega. 2023 May 24;8 (22) :20056-20065.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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