Antileishmanial agent-18

Antileishmanial agent-18 (Compound 1e) is an antileishmanial agent. Antileishmanial agent-18 effectively inhibits growth of L. donovani promastigotes. Antileishmanial agent-18 is safe for host cells[1].

Product Specifications

CAS Number

[1007567-02-3]

UNSPSC

12352005

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antileishmanial-agent-18.html

Solubility

10 mM in DMSO

Smiles

CC1=C(NC2=CC=CC=C2C1=O)C(N[C@H]([C@H](C(NCC3=CC=CC=C3)=O)O)CC4=CC=CC=C4)=O

Molecular Formula

C28H27N3O4

Molecular Weight

469.53

References & Citations

[1]Hassan AHE, et, al. Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies. Eur J Med Chem. 2023 Mar 15;250:115211.|[2]Hassan AHE, et al. Bestatin analogs-4-quinolinone hybrids as antileishmanial hits: Design, repurposing rational, synthesis, in vitro and in silico studies. Eur J Med Chem. 2023 Mar 15;250:115211.