Antifungal agent 51
Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1].
Product Specifications
CAS Number
[2896209-47-3]
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-51.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C(CSC2=NC3=C(N2)C=CC=C3)(CN4N=CN=C4)O)C=C1
Molecular Formula
C18H16FN5OS
Molecular Weight
369.42
References & Citations
[1]Ghobadi E, et al. Design, synthesis and biological activity of hybrid antifungals derived from fluconazole and mebendazole. Eur J Med Chem. 2023 Mar 5;249:115146.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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