Antifungal agent 51

Antifungal agent 51 (Compound 5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1].

Product Specifications

CAS Number

[2896209-47-3]

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antifungal-agent-51.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(C(CSC2=NC3=C(N2)C=CC=C3)(CN4N=CN=C4)O)C=C1

Molecular Formula

C18H16FN5OS

Molecular Weight

369.42

References & Citations

[1]Ghobadi E, et al. Design, synthesis and biological activity of hybrid antifungals derived from fluconazole and mebendazole. Eur J Med Chem. 2023 Mar 5;249:115146.