Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-inflammatory agent 41

Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS) -induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].

Product Specifications

CAS Number

[2896204-90-1]

UNSPSC

12352005

Target

Interleukin Related; NF-κB; TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis; Immunology/Inflammation; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-41.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(C(OC3=CC=C(C=C3)NC(C4=CN(C5=CC=CC=C5C4=O)C6=CC=CC=C6)=O)=CC=N2)C=C1OC

Molecular Formula

C33H25N3O5

Molecular Weight

543.57

References & Citations

[1]Jun Yang, et al. Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis. Eur J Med Chem. 2023 Mar 5;249:115144.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Brain Heart Infusion Agar
MF-0150086-01 100 mg

Brain Heart Infusion Agar

Ask
View Details
Brain Heart Infusion Agar
MF-0150086-02 250 mg

Brain Heart Infusion Agar

Ask
View Details
Brain Heart Infusion Agar
MF-0150086-03 50 mg

Brain Heart Infusion Agar

Ask
View Details
AMPK beta 1 Rabbit monoclonal antibody
E43S40316 100 µL

AMPK beta 1 Rabbit monoclonal antibody

Ask
View Details
hsa-miR-556-5p miRNA Agomir
MBS8311024-01 5 nmol

hsa-miR-556-5p miRNA Agomir

Ask
View Details
hsa-miR-556-5p miRNA Agomir
MBS8311024-02 10 nmol

hsa-miR-556-5p miRNA Agomir

Ask
View Details