TGR5 agonist 2
TGR5 agonist 2 (compound 19) is a potent TGR5 agonist with an EC50 value of 0.27 µM[1].
Product Specifications
UNSPSC
12352211
Target
G protein-coupled Bile Acid Receptor 1
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tgr5-agonist-2.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12C[C@H]([C@@]3([C@]([H])([C@@H](CCCC(NCCS(=O)(O[Na])=O)=O)C)CC[C@]3([C@@]1([C@@H]([C@@H]([C@@]4(C[C@@H](CC[C@@]42C)O)[H])CC)O)[H])[H])[H])C
Molecular Formula
C29H50NNaO6S
Molecular Weight
563.77
References & Citations
[1]Luxenburger A, et al. The discovery of 12β-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists. Eur J Med Chem. 2023 Mar 15;250:115143.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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