Anticancer agent 110
Anticancer agent 110 is an anticancer agent with in vitro anticancer activity and excellent anti-leukemia potency. Anticancer agent 110 is highly cytotoxic to K-562 lineage chronic myelogenous leukemia cells at nanomolar concentrations. Anticancer agent 110 causes DNA damage and leads to apoptosis[1].
Product Specifications
CAS Number
887349-03-3
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-110.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(N2N=NN=C2)C=C1)NC3=NC=C(CC4=CC=C(C=C4)F)S3
Molecular Formula
C18H13FN6OS
Molecular Weight
380.40
References & Citations
[1]Pokhodylo N, et al. Bioisosteric replacement of 1H-1,2,3-triazole with 1H-tetrazole ring enhances anti-leukemic activity of (5-benzylthiazol-2-yl) benzamides. Eur J Med Chem. 2023 Mar 15;250:115126. |[2]Pokhodylo N, et al. Bioisosteric replacement of 1H-1,2,3-triazole with 1H-tetrazole ring enhances anti-leukemic activity of (5-benzylthiazol-2-yl) benzamides. Eur J Med Chem. 2023 Mar 15;250:115126.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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