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M1/M2/M4 muscarinic agonist 3

Product Specifications

UNSPSC Description

M1/M2/M4 muscarinic agonist 3 (compound 45) is a muscarinic mAChR M1/M2/M4 agonist with EC50s of 3.2 nM, 32 nM and 1.7 nM, respectively[1].

Target Antigen

mAChR

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/m1-m2-m4-muscarinic-agonist-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C1COC1)N(C2)CC2(CC3)C[C@@H]3N(CC4)CCC4C5=CC(F)=CC=C5OC

Molecular Weight

402.50

References & Citations

[1]Thomson C G et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists[J]. ACS Medicinal Chemistry Letters, 2023.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-149733/M1-M2-M4-muscarinic-agonist-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-149733/

Clinical Information

No Development Reported

CAS Number

2640109-28-8

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