M1/M2/M4 muscarinic agonist 3
M1/M2/M4 muscarinic agonist 3 (compound 45) is a muscarinic mAChR M1/M2/M4 agonist with EC50s of 3.2 nM, 32 nM and 1.7 nM, respectively[1].
Product Specifications
CAS Number
2640109-28-8
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/m1-m2-m4-muscarinic-agonist-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1COC1)N(C2)CC2(CC3)C[C@@H]3N(CC4)CCC4C5=CC(F)=CC=C5OC
Molecular Formula
C23H31FN2O3
Molecular Weight
402.50
References & Citations
[1]Thomson C G et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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