Anti-inflammatory agent 65
Anti-inflammatory agent 65 (compound 29) is a Hederagonic acid derivative with potent anti-inflammatory activity. Anti-inflammatory agent 65 inhibits nitric oxide (NO) release. Anti-inflammatory agent 65 inhibits the nuclear translocation of IRF3 and p65, and disrupts the STING/IRF3/NF-κB signaling pathway, thereby attenuating the inflammatory response[1].
Product Specifications
CAS Number
3035442-58-8
UNSPSC
12352005
Target
NO Synthase; STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-65.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1(COC(CCCNC(CCCC[C@H]2SSCC2)=O)=O)C(CC[C@]3(C)[C@@]4([H])CC=C5[C@]6([H])CC(C)(C)CC[C@@](C(OCC7=CC=CC=C7)=O)6CC[C@](C)5[C@@](C)4CC[C@@]13[H])=O
Molecular Formula
C49H71NO6S2
Molecular Weight
834.22
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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