Ferroptosis-IN-5

Ferroptosis-IN-5 (compound 9c) is a ferroptosis inhibitor with iron-chelating and reactive oxygen species (ROS) scavenging activities[1].

Product Specifications

CAS Number

[2991058-60-5]

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ferroptosis-in-5.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=CC(/C=C/C(NN2C(C)=C(O)C(C=C2)=O)=O)=C1

Molecular Formula

C15H13FN2O3

Molecular Weight

288.27

References & Citations

[1]Changjun Zhang, et al. Novel 3-hydroxypyridin-4 (1H) -One derivatives as ferroptosis inhibitors with iron-chelating and reactive oxygen species scavenging activities and therapeutic effect in cisplatin-induced cytotoxicity. Eur J Med Chem. 2023 Nov 11:263:115945.