Antitumor agent-122

Antitumor agent-122 (Compound 5j) is an antitumor agent with good efficacy, limited toxicity and low resistance. Antitumor agent-122 has antiproliferative activity for MGC-803 cell, HepG2 cell, SKOV3 cell and T24 cell with IC50 values of 5.23 μM, 3.60 μM, 1.43 μM, 3.03 μM, respectively[1].

Product Specifications

CAS Number

[2378641-43-9]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-122.html

Solubility

10 mM in DMSO

Smiles

S=C(N1CCN(C2=CC=C(C3=C4C=CC=C32)C(N(CCN(C)C)C4=O)=O)CC1)SCC5=CC=CC=C5

Molecular Formula

C28H30N4O2S2

Molecular Weight

518.69

References & Citations

[1]Liang SM, et al. Discovery of 4- (N-dithiobenzyl piperazine) -1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistance. Eur J Med Chem. 2023 Nov 10;263:115937.