J6-3
J6-3 is an inhibitor of ICMT with an IC50 of 0.6 μM and has anticancer activity. J6-3 inhibits MDA-MB231 cells with an IC50 of 3.4 μM[1].
Product Specifications
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/j6-3.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCN1C(CN(CC)CC)=CC2=CC(C3=CC=C(C)C=C3)=CC=C12
Molecular Formula
C28H40N2
Molecular Weight
404.63
References & Citations
[1]Yang WS et al. Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents. Amino Acids. 2017 Sep;49 (9) :1469-1485.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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