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M1/M2/M4 muscarinic agonist 1

Product Specifications

UNSPSC Description

M1/M2/M4 muscarinic agonist 1 (Compound 42) is a muscarinic M4/M1/M2 agonist with EC50 values of 6.5, 26 and 210 nM for M4/M1/M2, respectively. M1/M2/M4 muscarinic agonist 1 can be used for research on mental diseases, such as schizophrenia, delusion, etc[1].

Target Antigen

mAChR

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/m1-m2-m4-muscarinic-agonist-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CC2(C[C@H](N3CCC(C4=CC=CC=C4OCC)CC3)CC2)C1)C5COC5

Molecular Weight

398.54

References & Citations

[1]Christopher G Thomson, et al. Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists. ACS Med. Chem. Lett. 2023. Nov 6.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-149704/M1-M2-M4-muscarinic-agonist-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-149704/

Clinical Information

No Development Reported

CAS Number

2640109-42-6

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