Beclin1-Bcl-2 interaction inhibitor 1
Beclin1-Bcl-2 interaction inhibitor 1 potently inhibits Beclin 1/Bcl-2 binding. Beclin1-Bcl-2 interaction inhibitor 1 can be used for the research of cancer and neurodegeneration[1].
Product Specifications
UNSPSC
12352005
Target
Bcl-2 Family; Beclin1
Type
Reference compound
Related Pathways
Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/beclin1-bcl-2-interaction-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
[H][C@]1(CC(C2=CC=C(NC(OC(C)C)=O)C=C2)=NN1C(C3=CC=C(Br)C=C3)=O)C4=CC=CC=C4
Molecular Formula
C26H24BrN3O3
Molecular Weight
506.39
References & Citations
[1]Pan YZ, et al. Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol. 2023 Oct 24;6 (1) :1080.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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