Beclin1-Bcl-2 interaction inhibitor 1

Beclin1-Bcl-2 interaction inhibitor 1 potently inhibits Beclin 1/Bcl-2 binding. Beclin1-Bcl-2 interaction inhibitor 1 can be used for the research of cancer and neurodegeneration[1].

Product Specifications

UNSPSC

12352005

Target

Bcl-2 Family; Beclin1

Type

Reference compound

Related Pathways

Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/beclin1-bcl-2-interaction-inhibitor-1.html

Solubility

10 mM in DMSO

Smiles

[H][C@]1(CC(C2=CC=C(NC(OC(C)C)=O)C=C2)=NN1C(C3=CC=C(Br)C=C3)=O)C4=CC=CC=C4

Molecular Formula

C26H24BrN3O3

Molecular Weight

506.39

References & Citations

[1]Pan YZ, et al. Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol. 2023 Oct 24;6 (1) :1080.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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