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D1N8

D1N8 is a potent SARS-CoV-2 3CLpro inhibitor with an IC50 and CC50 values of 0.44 μM and >20 μM, respectively. D1N8 has the potential for the research of anti-SARS-CoV-2 agents targeting 3CLpro[1].

Product Specifications

CAS Number

2894770-40-0

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/d1n8.html

Solubility

10 mM in DMSO

Smiles

NC(C1=CC=C(N(CC2=CN(CC3=CC=CC(Cl)=C3)N=N2)C(C4=O)=O)C4=C1)=O

Molecular Formula

C19H14ClN5O3

Molecular Weight

395.80

References & Citations

[1]Xiangyi Jiang, et al. Identification of novel 1,2,3-triazole isatin derivatives as potent SARS-CoV-2 3CLpro inhibitors via click-chemistry-based rapid screening. RSC Med Chem. 2023 Aug 17;14 (10) :2068-2078.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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