Bcl-2-IN-15
Bcl-2-IN-15 (Compound 13d) ) is a Bcl-2 inhibitor (IC50: 363 nM) . Bcl-2-IN-15 inhibits the proliferation ofNCI leukemia cancer cell line[1].
Product Specifications
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl-2-in-15.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(SC(NC(C2=CC=C(NCCC3=CC=CC=C3)C([N+]([O-])=O)=C2)=O)=N4)=C4C=C1)NC5=CC=C(C=C5)OCC6=CC=C(C(F)(F)F)C=C6
Molecular Formula
C37H28F3N5O5S
Molecular Weight
711.71
References & Citations
[1]Ismail HS, et al. Design, molecular modelling and synthesis of novel benzothiazole derivatives as BCL-2 inhibitors. Sci Rep. 2023 Sep 20;13 (1) :15554.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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