Bcl-2-IN-13
Bcl-2-IN-13 is a Bcl-2 inhibitor with an IC50 value of 17 nM. Bcl-2-IN-13 can be used in cancer research[1].
Product Specifications
CAS Number
[1421687-31-1]
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl-2-in-13.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(N[C@H](CCN(C)C)CSC2=CC=CC=C2)C([N+]([O-])=O)=C1)(NC(C3=C4C=C(N5CCN(CC6=C(C7=CC=C(Cl)C=C7)C=CC=C6)CC5)C=C3)=NS4(=O)=O)=O
Molecular Formula
C42H44ClN7O6S3
Molecular Weight
874.49
References & Citations
[1]Ismail HS, et al. Design, molecular modelling and synthesis of novel benzothiazole derivatives as BCL-2 inhibitors. Sci Rep. 2023 Sep 20;13 (1) :15554.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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