Lysyl hydroxylase 2-IN-2
Lysyl hydroxylase 2-IN-2 (compound 13) is a potent Lysyl hydroxylase 2 (LH2) inhibitor, with the IC50 of approximately 500 nM. Lysyl hydroxylase 2-IN-2 inhibits the migration in 344SQ WT cells, but not impedes the migration of the same cell line with an LH2 knockout cells[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lysyl-hydroxylase-2-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC(N2CCN(C)CC2)=C1)CC(C3=CC=NC=C3)=O
Molecular Formula
C19H21N3O2
Molecular Weight
323.39
References & Citations
[1]Juhoon Lee, et al.Unleashing the Potential of 1,3-Diketone Analogues as Selective LH2 Inhibitors. ACS Med. Chem. Lett. 2023, 14, 10, 1396–1403
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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