Nurr1 agonist 6

Nurr1 agonist 6 (compound 13) is a Nurr1 agonist with Kd value of 1.5 μM and EC50 value of 3 μM[1].

Product Specifications

CAS Number

[3033875-47-4]

UNSPSC

12352005

Target

Nuclear Hormone Receptor 4A/NR4A

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/nurr1-agonist-6.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(NC2=CC=NC3=C2C=CC(Cl)=C3)=C(C=C1)OCCN(C)C

Molecular Formula

C19H19Cl2N3O

Molecular Weight

376.28

References & Citations

[1]Sai M, et al. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J Med Chem. 2023 Oct 12;66 (19) :13556-13567.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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