Nurr1 agonist 6
Nurr1 agonist 6 (compound 13) is a Nurr1 agonist with Kd value of 1.5 μM and EC50 value of 3 μM[1].
Product Specifications
CAS Number
[3033875-47-4]
UNSPSC
12352005
Target
Nuclear Hormone Receptor 4A/NR4A
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nurr1-agonist-6.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(NC2=CC=NC3=C2C=CC(Cl)=C3)=C(C=C1)OCCN(C)C
Molecular Formula
C19H19Cl2N3O
Molecular Weight
376.28
References & Citations
[1]Sai M, et al. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J Med Chem. 2023 Oct 12;66 (19) :13556-13567.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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