Nurr1 agonist 5
Product Specifications
UNSPSC Description
Nurr1 agonist 5 (compound 5o) is a neuroprotective transcription factor Nurr1 agonist with a Kd of 0.5 μM and an EC50 of 3 μM[1].
Target Antigen
Nuclear Hormone Receptor 4A/NR4A
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nurr1-agonist-5.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(C=C2C(C=CN2)=C1)C(NC3=C(C=CC(Cl)=C3)OCCN(C)C)=O
Molecular Weight
392.28
References & Citations
[1]Minh Sai, et al. Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole. J Med Chem. 2023 Oct 12;66(19):13556-13567.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149608/Nurr1-agonist-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149608/
Clinical Information
No Development Reported
CAS Number
3033875-32-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
