KHK-IN-4
KHK-IN-4 (compound 14) is a potent ketohexokinase (KHK) inhibitor. KHK-IN-4 can be used for fructose metabolic disease research[1].
Product Specifications
CAS Number
3034829-40-5
UNSPSC
12352005
Target
Ketohexokinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/khk-in-4.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1CCN1C2=NC(N3CC[C@@H](C3)CCC(O)=O)=C4C(C(F)(CC4)F)=N2
Molecular Formula
C18H24F2N4O2
Molecular Weight
366.41
References & Citations
[1]Guodong Zhu, et al. Discovery of a Novel Ketohexokinase Inhibitor with Improved Drug Distribution in Target Tissue for the Treatment of Fructose Metabolic Disease. J Med Chem. 2023 Oct 12;66 (19) :13501-13515.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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