Chitin synthase inhibitor 14
Chitin synthase inhibitor 14 (compound 4n) is chitin synthase (CHS) inhibitor. Chitin synthase inhibitor 14 has antifungal activity while possessed the potency against drug-resistant fungal variants[1].
Product Specifications
CAS Number
2922114-19-8
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chitin-synthase-inhibitor-14.html
Solubility
10 mM in DMSO
Smiles
O=C1C2(CCCN2C(CN3CCN(C(C4=C(Cl)C=CC([N+]([O-])=O)=C4)=O)CC3)=O)CC5=CC=CC=C5N1
Molecular Formula
C25H26ClN5O5
Molecular Weight
511.96
References & Citations
[1]Liu L, et al. Novel spiro[pyrrolidine-2,3'-quinoline]-2'-one derivatives containing piperazine fragment as potential chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem. 2023 Nov 15;260:115777.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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