Aβ-IN-8

Aβ-IN-8 (compound 7e) is a potent inhibitor of the Aβ aggregation[1].

Product Specifications

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ-in-8.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(/C=N/C2=NC3=CC=C(OC(F)(F)F)C=C3S2)N(C)C=C1OCC4=CC=CC=C4

Molecular Formula

C22H16F3N3O3S

Molecular Weight

459.44

References & Citations

[1]Mohammad Hossein Asgarshamsi, et al. Synthesis of Some Benzothiazole Derivatives Based on 3-Hydroxypyridine-4-one and Benzaldehyde and Evaluation of Their β-Amyloid Aggregation Inhibition Using both Experimental Methods and Molecular Dynamic Simulation. Chem Biodivers. 2023 Sep 10:e202301113.