α-Glucosidase-IN-36
Product Specifications
UNSPSC Description
α-Glucosidase-IN-36 (compound 5g) is a potent α-glucosidase inhibitor, with an IC50 of 6.69 ± 0.18 μM, Ki and Kis of 1.65 μM and 4.54 μM, respectively. α-Glucosidase-IN-36 may inhibit α-glucosidase activity by binding with its active site as well as changing the secondary structure of α-glucosidase. α-Glucosidase-IN-36 can be used for type 2 diabetes mellitus (T2DM) research[1].
Target Antigen
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-36.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=C(/C=N/N2C(COC3=CC=CC=C3)=NN=C2SCC(NC4=CC=C(OCC)C=C4)=O)C=C1
Molecular Weight
566.47
References & Citations
[1]Luo S, et al. Design, synthesis, biological evaluation, and docking study of new triazole-phenylacetamide derivatives as α-glucosidase inhibitors. Bioorg Chem. 2023 Sep 6;141:106844.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-149579/α-Glucosidase-IN-36-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-149579/
Clinical Information
No Development Reported
CAS Number
3025234-94-7
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