Iscartrelvir
Iscartrelvir (WU-04) is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. Iscartrelvir has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV) [1].
Product Specifications
CAS Number
[2921711-74-0]
Product Name Alternative
WU-04
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H]1CCCC[C@H]1NC2=C([N+]([O-])=O)C=C(Br)C=C2C(NC)=O)C3=CN=CC4=CC=CC=C43
Molecular Formula
C24H24BrN5O4
Molecular Weight
526.38
References & Citations
[1]Wu J, et al. The molecular mechanism of non-covalent inhibitor WU-04 targeting SARS-CoV-2 3CLpro and computational evaluation of its effectiveness against mainstream coronaviruses. Phys Chem Chem Phys. 2023 Sep 13;25 (35) :23555-23567.. .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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