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HDAC8-IN-5

HDAC8-IN-5 (Compound 6a) is a HDAC8 inhibitor (IC50: 28 nM) . HDAC8-IN-5 can be used for cancer research[1].

Product Specifications

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac8-in-5.html

Solubility

10 mM in DMSO

Smiles

O=C(NN(C(C1=C2C=CC=C1)=O)C2=O)C([H])NC(CO)=O

Molecular Formula

C12H11N3O5

Molecular Weight

277.23

References & Citations

[1]Guzmán Ramírez JE, et al. Synthesis of N-aminophalimides derived from α-amino acids: Theoretical study to find them as HDAC8 inhibitors by docking simulations and in vitro assays. Chem Biol Drug Des. 2023 Aug 28.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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