HDAC8-IN-5
HDAC8-IN-5 (Compound 6a) is a HDAC8 inhibitor (IC50: 28 nM) . HDAC8-IN-5 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac8-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NN(C(C1=C2C=CC=C1)=O)C2=O)C([H])NC(CO)=O
Molecular Formula
C12H11N3O5
Molecular Weight
277.23
References & Citations
[1]Guzmán Ramírez JE, et al. Synthesis of N-aminophalimides derived from α-amino acids: Theoretical study to find them as HDAC8 inhibitors by docking simulations and in vitro assays. Chem Biol Drug Des. 2023 Aug 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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