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MAO-B-IN-24

MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B (IC50: 1.60 μM) . MAO-B-IN-24 also inhibited MAO-A (22.42 μM) ; at 10 μM concentration, it also reduced AChE and BChE activities to 54.58% and 88.43%[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mao-b-in-24.html

Solubility

10 mM in DMSO

Smiles

O=C1C2(CCCC2)N(CC3=CC=C(C#N)C=C3)C4=CC=CC=C41

Molecular Formula

C20H18N2O

Molecular Weight

302.37

References & Citations

[1]Perumal K, et al. An efficient method to access spiro pseudoindoxyl ketones: evaluation of indoxyl and their N-benzylated derivatives for inhibition of the activity of monoamine oxidases. RSC Adv. 2023 Aug 22;13 (36) :24925-24935.. .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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