BC-05
BC-05 is an orally active and potent inhibitor of CD13 and proteasome. BC-05 has an IC50 value of 0.13 μM for human CD13 and an IC50 value of 1.39 μM for the 20S proteasome. BC-05 can be used in multiple myeloma research[1].
Product Specifications
CAS Number
2260717-73-3
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bc-05.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)B1OC(C(CC(O)=O)(CC(O)=O)O1)=O)[C@@H](O)[C@H](N)CC2=CC=CC=C2
Molecular Formula
C21H29BN2O9
Molecular Weight
464.27
References & Citations
[1]Zhang J, et al. Discovery of a Novel Ubenimex Derivative as a First-in-Class Dual CD13/Proteasome Inhibitor for the Treatment of Cancer. Molecules. 2023 Aug 30;28 (17) :6343.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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