FGFR1 inhibitor-9
FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor (IC50s: 0.85 nM) . FGFR1 inhibitor-9 binds to the ATP-binding pocket of FGFR1. FGFR1 inhibitor-9 has anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr1-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
O=C1C(Cl)=C(NC2=CC=C(C(/C=C/C3=CC=C(OC)C(OC)=C3)=O)C=C2)C(C4=C1C=CC=C4)=O
Molecular Formula
C27H20ClNO5
Molecular Weight
473.90
References & Citations
[1]Ronnakorn Leechaisit, et al. Discovery of Novel Naphthoquinonehalcone Hybrids as Potent FGFR1 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling. ACS Omega 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC042228-500 1x 500 µL
MAPK14 (CPTC-MAPK14-1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details