IHC3

IHC3 is a competitive and reversible MAO-B inhibitor (IC50: 1.672 μM) . IHC3 can interact with the amino acid Cys172 of MAO-B. IHC3 can be used for neurological diseases research[1].

Product Specifications

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ihc3.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(NC(/C2=N\N=CC=CC3=CC=CC=C3)=O)C2=C1

Molecular Formula

C17H12FN3O

Molecular Weight

293.30

References & Citations

[1]Manoharan A, et al. Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease. Molecules. 2023 Aug 21;28 (16) :6167.