IHC3
IHC3 is a competitive and reversible MAO-B inhibitor (IC50: 1.672 μM) . IHC3 can interact with the amino acid Cys172 of MAO-B. IHC3 can be used for neurological diseases research[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ihc3.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(NC(/C2=N\N=CC=CC3=CC=CC=C3)=O)C2=C1
Molecular Formula
C17H12FN3O
Molecular Weight
293.30
References & Citations
[1]Manoharan A, et al. Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease. Molecules. 2023 Aug 21;28 (16) :6167.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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