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Harmaline analog

Harmaline analog (compound 3) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.145 μM[1].

Product Specifications

CAS Number

2411677-02-4

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/harmaline-analog.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(CN2C3=C(C4=C2C(C)=NCC4)C=C(OC)C=C3)C=C1

Molecular Formula

C20H19ClN2O

Molecular Weight

338.83

References & Citations

[1]Uddin MJ, et al. Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. ACS Med Chem Lett. 2020 Feb 14;11 (10) :1881-1885.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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