Harmaline analog
Harmaline analog (compound 3) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.145 μM[1].
Product Specifications
CAS Number
2411677-02-4
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/harmaline-analog.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(CN2C3=C(C4=C2C(C)=NCC4)C=C(OC)C=C3)C=C1
Molecular Formula
C20H19ClN2O
Molecular Weight
338.83
References & Citations
[1]Uddin MJ, et al. Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. ACS Med Chem Lett. 2020 Feb 14;11 (10) :1881-1885.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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