PI5P4K-β-IN-2

PI5P4K-β-IN-2 (compound d5) is a PI5P4K-β inhibitor (IC50 = 0.35 μM) with antitumor activity.

Product Specifications

UNSPSC

12352005

Target

PI5P4K

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi5p4k-β-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C1NC(NC2=CC=CC(C#N)=C2)=N/C1=C/C3=CC=CC(OCC4=CC=C(Cl)C=C4Cl)=C3

Molecular Formula

C24H16Cl2N4O2

Molecular Weight

463.32

References & Citations

[1]Wei L, Xu M, Liu Z, Jiang C, Lin X, Hu Y, Wen X, Zou R, Peng C, Lin H, Wang G, Yang L, Fang L, Yang M, Zhang P. Hit Identification Driven by Combining Artificial Intelligence and Computational Chemistry Methods: A PI5P4K-β Case Study. J Chem Inf Model. 2023 Aug 28;63 (16) :5341-5355.