Mal-PEG8-Val-Ala-PAB-SB-743921
Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs[1].
Product Specifications
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg8-val-ala-pab-sb-743921.html
Purity
99.28
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
Molecular Formula
C73H96ClN7O19
Molecular Weight
1411.03
References & Citations
[1]Li Y, et al. A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo. Biomaterials. 2023 Jul 28;301:122258.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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