FHND5071
FHND5071 is a potent and selective RET kinase inhibitor, FHND5071 can exert antitumor effects by inhibiting RET autophosphorylation. FHND5071 can be used for tumor diseases research[1].
Product Specifications
CAS Number
2761152-16-1
UNSPSC
12352005
Target
RET
Type
Isotope-Labeled Compounds
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Others; Cancer
Solubility
10 mM in DMSO
Smiles
N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(N7CCN(C([2H])([2H])[2H])CC7)=CN2N=C1
Molecular Formula
C30H30D3N9O
Molecular Weight
538.66
References & Citations
[1]Han Y, et al. Preclinical Pharmacokinetics and in vitro Metabolism of FHND5071, a Novel Selective RET Kinase Inhibitor. Eur J Drug Metab Pharmacokinet. 2023 Sep;48 (5) :595-614.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
Phase 1
Frequently Asked Questions
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