MAOA-IN-1

MAOA-IN-1 (compound 15) is an orally active MAOA inhibitor with cytotoxicity against prostate cancer cells. MAOA-IN-1 has Caco-2 permeability and lower CNS permeability. MAOA-IN-1 can be further used in the research of anti-cancer and anti-inflammatory indications[1].

Product Specifications

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/maoa-in-1.html

Solubility

10 mM in DMSO

Smiles

OC(CN(C)CC#C)COC1=CC(N)=C(Cl)C=C1Cl

Molecular Formula

C13H16Cl2N2O2

Molecular Weight

303.18

References & Citations

[1]Jacobs MR, et al. Synthesis and anti-cancer potential of potent peripheral MAOA inhibitors designed to limit blood:brain penetration. Bioorg Med Chem. 2023 Sep 7;92:117425.