FXIIa-IN-2
FXIIa-IN-1-IN-2 (Compound 21) is a Factor XIIa inhibitor (Kiapp: 62.2 nM) . FXIIa-IN-1-IN-2 can be used for research of thrombosis[1].
Product Specifications
CAS Number
3052551-17-1
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/fxiia-in-2.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(OC(C(C(OC3=CC4=CC=C(C(N)=N)C=C4C=C3)=O)=C2)=O)C=C1OC
Molecular Formula
C23H18N2O6
Molecular Weight
418.40
References & Citations
[1]Davoine C, et al. Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy. Eur J Med Chem. 2023 Jul 16;259:115636.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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